Yale University scientists have succeeded in restoring basic cellular activity i...
- Yale University scientists have succeeded in restoring basic cellular activity in pigs’ brains hours after their deaths in a finding that may one day lead to advances in treating human stroke and brain injuries, researchers reported on Wednesday.
Still, the study raises a host of bioethical issues, including questions about the very definition of brain death and potential consequences for protocols related to organ donation. Results of the experiment, to be published on Thursday in the journal Nature, run contrary to long-accepted principles of brain death, which hold that vital cellular activity ceases irreversibly seconds or minutes after oxygen and blood flow are cut off.
It was in the lab run by Sestan, a Yale professor of neuroscience, comparative medicine, genetics and psychiatry, that researchers developed the so-called BrainEx system used to pump artificial nutrients into the pig brains’ vascular network.Scientists stressed, however, that the treated brains still lacked any detectable signs of organised electrical activity associated with perception, awareness or consciousness.
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