Yale University scientists have succeeded in restoring basic cellular activity i...
- Yale University scientists have succeeded in restoring basic cellular activity in pigs’ brains hours after their deaths in a finding that may one day lead to advances in treating human stroke and brain injuries, researchers reported on Wednesday.
The research grew out of efforts to enhance the study of brain development, disorders and evolution. The main practical application is the prospect of allowing scientists to analyze whole brain specimens of large mammals in three dimensions, rather than through studies confined to small tissue samples, Yale said.
The limited rejuvenation of circulatory function and cellular metabolism in pig brains, which were harvested from animals slaughtered at a meat-packing plant, was achieved four hours after death by infusing the brains with a special chemical solution designed to preserve the tissue. “Clinically defined, this is not a living brain, but it is a cellularly active brain,” study co-author Zvonimir Vrselja, associate researcher in neuroscience.
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