World's hottest chili pepper, the Carolina Reaper, ignites sudden and severe Thunderclap headache.
In the first reported case of its kind, a 34-year-old man competing in a chili pepper–eating contest experienced a sudden thunderclap headache after ingesting a single"Carolina Reaper," which is widely considered the world's hottest chili pepper.
After experiencing dry heaves without vomiting, the man developed intense neck and occipital pain that become holocephalic. The excruciating pain drove him to seek emergency department care. He had at least two more episodes of brief thunderclap headache over the ensuing days. Initial diagnostic tests came back negative. His urine drug screen and noncontrast head and neck computed tomography scans were unremarkable. He had no neurologic deficits, and his blood pressure was 134/69 mm Hg.
Although CT angiography did not show an aneurysm, it did reveal a surprise. Doctors detected multifocal luminal narrowing in his left supraclinoid internal carotid artery, M1 segment of bilateral middle cerebral arteries, and P1 segments of bilateral posterior cerebral arteries — a finding consistent with vasospasm.
"A few cases have been reported regarding coronary vasospasm and myocardial infarction caused by ingestion of cayenne pepper and use of topical capsaicin patch," Kulothungan Gunasekaran, MD, from the Division of Hospital Medicine at Henry Ford Hospital in Detroit, Michigan, told"To the best of our knowledge after extensive literature search, our case is the first to report cerebral vasospasm leading to reversible cerebral vasoconstriction syndrome [RCVS] after ingestion of the...
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