A good night’s sleep is good for the soul.
connecting the brain and bloodstream—replaces toxin-filled fluid with fresh liquid primarily during deep sleep. When this waste management system underperforms due to a lack of Z’s, it’s like when you forget to take the trash out to the curb. Once in a while, it’s not a big deal, but if you let it build up, your home will start to experience all kinds of unrelated problems.
“This drug is already available and proven safe, and now we have evidence that it affects the levels of proteins that are critical for driving Alzheimer’s disease,” he said. After a day and a half, participants who received the higher dose of suvorexant and got a good night’s sleep had 10-20 percent lower levels of beta-amyloid than participants who didn’t receive the medication. The proportion of phosphorylated tau protein—another marker of Alzheimer’s—was 10-15 percent lower in the high-dose group compared to the no-dose one.
“If we can lower amyloid every day, we think the accumulation of amyloid plaques in the brain will decrease over time,” he said.
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