Fewer than 50 people in the world have it.
In some cases, the Rh-null blood runs in families, which makes sense due to its genetic component.
This is a condition that occurs when the mother's immune system reacts against the Rh antigens in the fetus's red blood cells. As a result, the newborn can have anemia, severe jaundice, swelling , an enlarged liver or spleen, etc. In severe cases, HDFN can even cause stillbirth or neonatal death. If they don’t receive the medication in time and they develop antibodies for Rh antigens, then any future babies will be at risk of developing HDFN.People with Rh-null blood do not have any type of Rh antigens; therefore, they can’t receive blood from a person who has them . If they do, they can develop an adverse immune reaction called Hemolytic Transfusion Reaction .
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