New MRI technique may be a breakthrough that allows doctors to better guide treatment strategies and treatment in stiff heart syndrome. CardioTwitter theheartorg
Then they assessed the technique in a prospective observational study in a subset of newly diagnosed AL amyloidosis patients enrolled in the Centre’s larger
By being able to assess the success of chemotherapy treatment in this way, they could detect which patients would have a better or worse prognosis. Furthermore, combining the MRI results with blood tests, they found that almost 40% of patients had a substantial improvement in amyloid deposition, something that was not thought to be possible before and that showed just how effective chemotherapy can be in cardiac amyloidosis.
"This is incredibly valuable for clinicians; knowing the amount, rather than just the presence of amyloid, means they can better guide treatment options, by more accurately deciding timing and protocol of second line chemotherapy treatments."Senior author, Professor Marianna Fontana, also from UCL's Division of Medicine, said that the MRI technique should now be used immediately to diagnose and assess all cases of light-chain cardiac amyloidosis.
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