Have you ever suffered from jet lag or struggled after turning the clock forward or back an hour for daylight saving time? These are examples of you feeling the effects of what researchers call your biological clock, or circadian rhythm – the “master pacemaker” that synchronizes how your body respon
Getting the most out of exercise
To investigate this, my colleagues and I collected blood and tissue samples from the brains, hearts, muscles, livers, and fat of mice that exercised either before breakfast in the early morning or after dinner in the late evening. We used a tool called a mass spectrometer to detect approximately 600 to 900 molecules each organ produced. These metabolites served as real-time snapshots of how the mice responded to exercise at specific times of day.
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