The idea involves a controversial type of medical study known as a human challenge trial.
Scientists are surging forward with possible COVID-19 vaccines, including here in San Diego. But they’ve still got a long way to go.
But there’s a lot of opposition and concern about HCTs in the scientific community, and some think a useful trial of that sort would take as long to design as developing a successful vaccine. Dr. Davey Smith, director of infectious diseases and global public health at UC San Diego, said “there is no potential clinical benefit for participating in the study. The participant has nothing to gain except altruism ...“I would feel better if there was a treatment for coronavirus if/when an infection occurred, like we have for malaria.”
As that was happening, the National Institutes of Health was releasing a report that said the timeline for developing a robust HCT “that meets the essential criteria for limiting risk for study volunteers could take one to two years.”“The authors conclude that large, randomized, controlled trials of SARS-CoV-2 are the fastest and most effective path forward for establishing vaccine safety and efficacy,” the report said.
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