Surgically attaching old mice to young mice to exchange their blood has previously been shown to rejuvenate the older individuals' brains, livers and muscles. Now, it has been shown to also extend their lifespan, even after the animals have been detached
clocks, which analyse patterns of markers on DNA called methyl groups that correlate with age, to find out whether the old mice that were connected to young mice became biologically “younger”. Indeed, straight after detachment and even two months later, they appeared up to 30 per cent younger than those that had been joined to old mice.
Discontinuing therapy: completed 6, 1L young plasma exchanges. 1x/mo . Evaluated biomarkers from biofluids, devices and imaging, no benefits detected.
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