In 2007, Yale pediatric neurosurgeon, Dr. Steven Schiff, visited his colleague Dr. Benjamin Warf at the CURE Children’s Hospital in Uganda. The scenes at the hospital stunned him: every day mothers came from all over the country carrying infants with enlarged heads, desperate for a cure. The moth
pediatric neurosurgeon, Dr. Steven Schiff, visited his colleague Dr. Benjamin Warf at the CURE Children’s Hospital in Uganda. The scenes at the hospital stunned him: every day mothers came from all over the country carrying infants with enlarged heads, desperate for a cure.
There is no known cure, and the need to relieve pressure on the brain forms the most common indication for neurosurgery in infancy worldwide. East Africa had become a hotbed for pediatric hydrocephalus for mysteriously unknown reasons, with an estimated 4,000 new cases in Uganda alone each year. And although it was possible to use advanced gene sequencing methods to identify bacteria that would not grow in culture, those technologies were both expensive and not readily available in Uganda. This combination of challenges made the question of what was causing all these cases of postinfectious hydrocephalus in Ugandan babies daunting. But Schiff was determined to tackle this mystery, believing that it was a solvable problem.
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