Why Antidepressants Take So Long to Work

Malaysia News News

Why Antidepressants Take So Long to Work
Malaysia Latest News,Malaysia Headlines
  • 📰 WIRED
  • ⏱ Reading Time:
  • 26 sec. here
  • 2 min. at publisher
  • 📊 Quality Score:
  • News: 14%
  • Publisher: 51%

A clinical trial reveals the first evidence of how the brain restructures physically in the first month on SSRIs—and the link between neuroplasticity and depression.

Clinical depression is considered one of the most treatable mood disorders, but neither the condition nor the drugs used against it are fully understood. First-line SSRI treatments likely free up more of the neurotransmitter serotonin to improve communication between neurons. But the question of how SSRIs enduringly change a person’s mood has never returned completely satisfying answers. In fact, SSRIs often don’t work.

In this case, the labels were designed to stick to a protein at the connection between neurons. Tracing them would map out the brain’s synapses, allowing scientists to measure synaptic density. Their hypothesis was simple: The participants who took the drug instead of the placebo would show more synaptic density. That hypothesis was wrong. “At first glance, it seemed slightly disappointing,” Knudsen says. There was no significant difference between synapses in the drug and placebo cohorts.

We have summarized this news so that you can read it quickly. If you are interested in the news, you can read the full text here. Read more:

WIRED /  🏆 555. in US

Malaysia Latest News, Malaysia Headlines

Similar News:You can also read news stories similar to this one that we have collected from other news sources.

Why a 3,000-mile-long jet stream on Jupiter surprised NASA scientistsWhy a 3,000-mile-long jet stream on Jupiter surprised NASA scientistsLaura is a science news writer, covering a wide variety of subjects, but she is particularly fascinated by all things aquatic, paleontology, nanotechnology, and exploring how science influences daily life. Laura is a proud former resident of the New Jersey shore, a competitive swimmer, and a fierce defender of the Oxford comma.
Read more »

Why Pixar Spent So Long Making One of Its Most Beloved FilmsWhy Pixar Spent So Long Making One of Its Most Beloved FilmsWALL-E took Pixar fourteen years to make, making it the longest the animation company has ever taken with a film. But why?
Read more »

Why New Serotonin Research Could Be A Game Changer For Long CovidWhy New Serotonin Research Could Be A Game Changer For Long CovidDr. Omer Awan MD MPH CIIP is a practicing radiologist physician in Baltimore, MD that writes about healthcare and public health. He earned his Medical Doctor (MD) degree from the George Washington University School of Medicine and Health Sciences and his Master in Public Health (MPH) degree from Harvard University.
Read more »

Long Island teacher uses classroom pets to teach first graders social & emotional needs along with scienceLong Island teacher uses classroom pets to teach first graders social & emotional needs along with scienceAccording to Pet Care Trust, which offers grants to educators to sponsor pets in classrooms, requests are up 36%.
Read more »

Second trial over Long Island anti-gang activist’s killing ends in mistrialSecond trial over Long Island anti-gang activist’s killing ends in mistrialAnnmarie Drago's second trial over the death of anti-gang activist Evelyn Rodriguez has ended with jurors failing to reach a verdict on a criminally negligent homicide charge.
Read more »

What Michael Cohen said about his testimony and why it matters in the Trump fraud trialWhat Michael Cohen said about his testimony and why it matters in the Trump fraud trialAn apparent backtrack by Donald Trump’s ex-lawyer and fixer Michael Cohen threw the New York civil fraud trial into more chaos Wednesday afternoon.
Read more »



Render Time: 2025-08-25 06:05:11