What the FDA Ruling about 'Dense Breasts' Means for Cancer Risk and Screening

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What the FDA Ruling about 'Dense Breasts' Means for Cancer Risk and Screening
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Women with dense breasts are at higher risk of breast cancer and are underdiagnosed, but other factors also play an important role

rule that requires mammography facilities to notify women about their breast density

Women with dense breasts can develop cancers that can’t be seen on a mammogram. Both dense breast tissue and tumors appear white on a mammogram, which can mask cancers. In fatty tissue, which appears gray, white tumors are more apparent. But because a minority of women are considered high risk based on breast density alone, many doctors caution that breast density notification laws have so far, wrote Jennifer Haas, now at Massachusetts General Hospital, and Celia Kaplan of the University of California, San Francisco, in a 2015 paper in“Such laws also do not address other important risk factors for breast cancer such as age, family history of breast or ovarian cancer,and other genetic mutations, or prior breast biopsy,” Haas and...

MRI combined with mammography is generally the most effective screening protocol for women with dense breasts because MRI is highly accurate and results in fewer false positives than ultrasound, Berg says. But MRI doesn’t eliminate the risk of false positives entirely, she adds. Several studies of MRI screening for people with dense breasts have

“It’s attractive because there’s no tunnel, and it can be done with existing equipment with usually a software upgrade,” Berg says. “Additionally, contrast-enhanced mammography may be something that can be much more widely available and probably less expensive by far than MRI because the contrast is inexpensive.”

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