What is microRNA? Nobel-winning discovery explained, medical breakthroughs possible

Nobel Prize News

What is microRNA? Nobel-winning discovery explained, medical breakthroughs possible
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PARIS, Oct 8 — The Nobel Prize in Medicine was awarded yesterday to two US scientists for discovering microRNA, a previously unknown type of genetic switch which is hoped can...

In 2010, just a tenth of Malaysian degree holders worked in low-paid jobs — By 2022, it has almost tripled, according to World Bank

And the world paid little attention when the new Nobel laureates Victor Ambros and Gary Ruvkun revealed their discovery decades ago, thinking it was just “something weird about worms”, Cambridge University geneticist Eric Miska told AFP.Each cell in the human body has the same set of instructions, called DNA. Some turn into brain cells, while others become muscles.

Miska gave the example of the messenger RNA vaccines rolled out against Covid-19 during the pandemic, which insert a message with new instructions to build proteins that block viruses. “This was a whole new level of control that we had totally missed,” said Miska, who has worked on microRNA for two decades, including with the new Nobel laureates.

“Nobody really paid much attention,” Miska said, explaining that most scientists at the time thought it only applied to worms. “Though there are no very clear applications available yet in microRNAs, understanding them, knowing that they exist, understanding their counter-regulatory networks, is always the first step,” the Karolinska Institute’s Gunilla Karlsson Hedestam told journalists in Stockholm.

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