Weight loss drug reverses obesity for nearly half of teens in study

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Weight loss drug reverses obesity for nearly half of teens in study
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Semaglutide was recently approved by the FDA to help obese adolescents lose weight. When used to treat diabetes, the drug is sold under the brand name Ozempic.

that a weekly self-administered injection of Wegovy or Ozempic, which are manufactured by Danish pharmaceutical giant Novo Nordisk, can be effective in reducing body weight — more so than older generations of diet pills — and lowering some of the health risks associated with obesity.The U.S. Food and Drug Administration first approved Ozempic to treat Type 2 diabetes. The agency approved Wegovy’s use as a treatment for chronic weight management in adults in 2021 and in teens late last year.

“It’s a different way to describe the outcomes in more clinically relevant way,” said Kelly, who also co-wrote the December paper. Semaglutide works by mimicking the naturally occurring hormone GLP-1, or glucagon-like peptide 1, to target receptors in the brain, reduce a patient’s appetite and slow the passage of meals through the gut.It helps to “normalize the body systems related to eating and energy regulation. It essentially takes the edge off,” Kelly said.

Doctors are touting the drug as the latest in a new generation of weight-loss medication that could help patients struggling with chronic weight management.about 22 percent of Americans ages 12 to 19 are obese. Among adults, the rate rises to 42 percent. Being overweight or obese increases the lifelong risk of many health conditions and diseases, including Type 2 diabetes, certain cancers, stroke and heart disease.

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