Fentanyl is potent and very addictive, and an alarming amount of it is being sold illegally in the US. But blocking the study of 'fentanyl-related substances' isn't helping – it's halting potentially lifesaving research, says chemist GregoryDudley10
In the US, the Drug Enforcement Administration classifies drugs into five different categories, or “schedules”, depending on their medical value and potential for abuse. The lower the number, the more closely regulated the substance, and the harsher the penalties for illicit use or sale. Schedule I is reserved for drugs with no safe, accepted medical use and high abuse potential.Fentanyl itself is a Schedule II drug.
The intent of all this may be to deter development of illicit drugs, but the impacts are broader and more complex. The singular defining characteristic of a “fentanyl-related substance” is molecular structure – not function, potency or abuse potential. Structure is important, but function is the larger concern here.
Could fentanyl-related research produce new and possibly better lifesaving interventions? We won’t know unless we do the work, but there are already promising signs. The US National Institute on Drug Abuse looked internally at a small handful of fentanyl-related substances and
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