Two probiotics identified as promising hypertension treatments

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Two probiotics identified as promising hypertension treatments
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New findings point to 2 additional probiotics as potential treatments for high blood pressure.

An estimated 40% of the global adult population have high blood pressure, or hypertension, which puts people at risk of cardiovascular disease and other dangerous health conditions. Recent studies suggest that probiotics may offer a protective effect, but researchers have a limited understanding of why shaping the gut microbiota can regulate blood pressure.adds 2 new strains to the list of potential antihypertensive probiotics.

In the new study, the researchers tested the 2 probiotic strains on mice that developed high blood pressure after consuming water mixed with fructose. Over 16 weeks, they measured the animals' blood pressures every 4 weeks. They found that fructose-fed mice that received either probiotic showed significantly lower blood pressures than those fed a high fructose diet and not treated with probiotics.

The researchers used shotgun metagenomic sequencing to probe connections between the altered gut microbiota and the change in blood pressure. They found that a high-fructose diet in the mice led to an increase in Bacteroidetes and a decrease in Firmicutes bacteria; however, treatment with probiotics returned those populations to those found in the control group.

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