Scientists have made a drug based on LSD that seems to fight depression without producing a psychedelic experience.
The team decided to focus on molecules that affect the brain's serotonin system, which is involved in regulating a person's mood. But they still weren't looking for an antidepressant.
"There [were] really interesting reports about people getting great results out of this after just a few doses," says, an author of the study and a professor in the pharmaceutical chemistry department at the University of California, San Francisco. The team says it needs to refine these new molecules before they can be tried in people. One reason is that they appear to mimic LSD's ability to increase heart rate and raise blood pressure.
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