Avian influenza can wipe out entire poultry flocks. An early experiment with Crispr suggests that gene editing can protect chickens against infection.
A growing number of countries are starting to vaccinate chickens against bird flu, while the United States and United Kingdom are still holding out because of uncertainties about immunization’s cost and effectiveness. Meanwhile, researchers in the UK have come up with another possible approach to protecting poultry flocks: gene editing.
The team also wanted to make sure those changes wouldn’t cause more severe infection in people, so they added the mutated viruses to human airway cells that had been cultivated in a dish. They found that the mutations didn’t help the virus grow in a way that would pose an increased risk to people. It’s also not known how the gene-edited chickens will fare against the much more aggressive bird flu strains such as H5N1, which weren’t tested in the study.
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