The discovery could lead to potential future targeted therapies and treatments for this brain disorder.
Researchers have found two novel genes that increase an individual’s risk of developing Alzheimer’s disease . This disorder is the leading cause of dementia and has an estimated heritability —genetic factor causing variation in the population, or an inherited trait— of 70%.The research team worked with Cardiff University's Dementia Research Institute in the U.K. to reveal the new genes associated with the brain disorder that affects thinking and behavior, often starting with memory loss.
Researchers believe that the study allows them to assess variance in the immune system and brain processing. "These findings point us towards very specific processing in the brain, which includes differences in the brain's immune system and how the brain processes cholesterol.
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