WASHINGTON, May 22 (Reuters) - Prominent U.S. law firm Fenwick & West, which advised FTX before its 2022 blockbuster collapse and bankruptcy, on Friday said it will pay $54 million to resolve claims from FTX customers who alleged the firm helped enable one of the largest financial frauds in U.S. history.
Brandon gets a post-surgery checkup for his implanted brain-computer interface at the University of Colorado. — TNS To say Brandon Patterson’s father wasn’t fully on board when he first brought up the idea of having electrodes implanted into his brain would be an understatement – and their family doesn’t mince words.
Brandon, 41, already relies on his dad for all of his daily needs, ranging from setting up the lift to move him from bed to his wheelchair, to scrubbing him down in the shower and pouring his morning coffee into a cup with a straw. That was the way it has been since Brandon broke his neck in a vehicle accident almost nine years earlier, and they made it work, with a hefty dose of gallows humour to keep from screaming.
Monty Patterson trusted the doctors at UCHealth knew what they were doing, but opening someone’s skull always carries the risk of doing further damage. What would happen if Brandon lost control of the limited muscles he could use in his arms or his ability to speak?
“I said, ‘If you’re just doing this so you can play video games, I’m gonna smack you,’” Monty said in an interview at the University of Colorado Hospital in Aurora, United States, while Brandon was hooked up to a computer tracking his brain activity. Testing a different area Brain-computer interfaces that allow people to control artificial limbs using their minds exist at the boundary of science and science fiction.
As it stands, a paralysed person who has had the surgery and undergone the lengthy process of training the program can control objects on a screen and complete some movements with a robotic arm. But a system that would allow patients to regain the full abilities they had before their injuries – while possible – remains only a hope.
Brandon, who is paralysed from the chest down and has limited use of his arms, was the first person in the American state of Colorado to have a brain-computer interface implanted into a part of his brain involved in decision-making during a surgery in February . The researchers working with him aim to determine whether putting electrodes there – rather than in areas specific to movement – will produce better control of screens or artificial limbs.
They are also investigating whether they can send signals the other way, to produce semi-natural sensations in limbs that can’t communicate with the brain. University of Colorado Anschutz Medical Campus assistant professor of neuroscience Dr Daniel Kramer implanted six arrays of electrodes, which resemble patches of tiny needles, to pick up signals from the surface of Brandon’s brain.
A computer then has to learn how to decode what the electric signals in the brain mean, because two people thinking about the same action produce different patterns. The current setups are good at moving a robotic arm in the right direction, but don’t always know when to stop – something like a toddler who knocks over the toy they want to grab, Asst Prof Kramer explained.
Putting the electrodes in a part of the brain involved in higher processing might improve that, he said. If a computer could send signals back, the brain could judge whether it needs to tighten or loosen the grip of a robotic arm, in the same way that a person using their natural hand finds the balance where they don’t crush or drop the thing they’re holding, he added.
ALSO READ:Private companies and researchers are working on parallel tracks with the technology, with the businesses trying to prove their products help patients enough that the US Food and Drug Administration should approve them, Asst Prof Kramer said. At universities, they’re more focused on learning about how the technology and the brain work together, which could lay the groundwork for future advances, he said.
Asst Prof Kramer made clear that he couldn’t guarantee any benefits and that the goal of the research was to improve the technology for future patients, Brandon said. He doesn’t have any robotic devices or a computer capable of linking to his brain at home, so he only uses the technology during sessions with the research team.
Brandon’s wildest dream for the brain-computer interface is to someday be able to drive his wheelchair with his mind, like Professor X in theBut being able to use a computer more easily would also be a significant improvement, he said. He currently uses a combination of voice controls and a stylus that attaches to his hand like a brass knuckle, allowing him to peck at a screen.
Neither was enough to succeed with Microsoft Excel and pass the statistics class he took as part of his psychology major at Red Rocks Community College, he said. On a Friday in April , researchers hooked Brandon up to a computer, plugging wires into ports sticking out of his scalp like a stegosaurus’ back.
“If I’m going to get looked at funny because I’ve got spikes, I’m going to make it as punk rock as possible,” he said. Set-up complete, the researchers assigned Brandon mental tasks, such as visualising putting his fingers through the holes of a pair of scissors or holding a cup.
Just thinking about the tasks didn’t produce a significant reaction that they could detect, but holding up the scissors as a visual aid and asking him to pretend he wanted to drink from the imaginary cup got the signals firing. Later, they set up something that looked like a 1980s computer game, with a green disc sliding on top of gray discs in a circle around it.
The researchers were moving the green disc at that point while telling Brandon to imagine sending it in the right direction, Asst Prof Kramer said. Eventually, once the computer learns to decode his brain’s patterns, he’ll be able to move the virtual disc with his thoughts. When he tried again, about two weeks later, Brandon could move the disc without as much support from the computer.
He couldn’t budge it when asked to imagine he was playing air hockey, but a prompt to think about how the Jedi move things with their minds in theRegaining her voice through a brain implantPeople can somewhat understand the challenges of not being able to use his arms fully or his legs at all, but having quadriplegia brings a whole different set of challenges that a brain-computer interface probably can’t solve, said Tammy Neuman, Monty’s partner and Brandon’s co-caregiver.
Brandon – who lives with his father and Neuman in Elbert, about 50 miles south-east of Denver in Colorado – had to relearn how to cough because his diaphragm no longer contracted and figure out what he could do with limited control of his arms.
“Life with a quadriplegic is always about overcoming,” she said. On top of that, the stillness can lead to blood clots, including one that went into his lungs and landed him in the hospital, Brandon said. Something as comparatively minor as a full bladder or bowel can trigger a dangerous spike in blood pressure because his body senses something is wrong below his spinal injury and doesn’t know how to manage it.
“I say I’m on 13 of my nine lives,” Brandon said. – By Meg Wingerter/The Denver Post/Tribune News Service
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