Antibiotic resistant microbes from the soil, from aquaculture, from sewage and from hospitals can hook onto air pollution particles. A new study looks at the implications.
highlights a surprising potential vector for the spread of antimicrobial resistance : air pollution.
Using data from published studies as well as disease surveillance networks, clinical trials and diagnostic labs, the researchers tried to untangle which factors were most important in driving up global antimicrobial resistance over the period from 2000-2018 . Ultimately, they say the air pollution association accounts for some 12% of the increase during that time, adding up to 480,000 premature deaths and economic costs of $395 billion in 2018 alone.
Ultimately all that material doesn't stay in the soil or the waterways but catches rides on particles and aerosols into the air, where people can inhale them. The study nails down an association between particulate air pollution and AMR, but the researchers say it does not establish causality or reveal the biological mechanism at play. Elena Buelow,at the University of Grenoble Alpes in France, says it's an important relationship to probe, but she's yet not convinced that air pollution is the ultimate culprit.
For Buelow, it will be important to more firmly establish what the actual mechanism is for spreading AMR to actual people through the air.
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