LANZHOU: Bacterial therapy could offer a promising new method for the prevention and treatment of colorectal cancer, according to a study carried out ...
: Bacterial therapy could offer a promising new method for the prevention and treatment of colorectal cancer, according to a study carried out by Chinese researchers, Xinhua reported.
Professor Li Xiangkai, head of the research group and a professor at the university’s School of Life Sciences, explained that studies have shown that colorectal cancer patients often experience an imbalance in their gut microbiota and a persistent state of peroxidation in tumor cells. Unlike conventional antioxidants, probiotics like Lactobacillus GR-3 could specifically target the tumor microenvironment while also regulating intestinal flora.
The results showed that Lactobacillus GR-3 significantly reduced the growth of colon tumors in drug-induced mice and demonstrated positive therapeutic effects. The strain not only lowered tumor mass but also improved the composition of intestinal microbial metabolites, promoted apoptosis in colon cancer cells, and inhibited their proliferation.
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