In a recent small study, the antidepressant effects of ketamine lasted longer when an intravenous dose was followed with computer games featuring smiling faces or words aimed at boosting self-esteem.
Established drugs like Prozac and Zoloft can take weeks to ease depression, and don't work for every patient. Ketamine can offer immediate relief, but the effects often fade after a few days or weeks.
The team had some participants play special computer games for 30 to 40 minutes a day for four days after they received an infusion of ketamine.In games that involved words, every time a player saw the letter"I" it was followed by positive terms like"good, lovable, sweet, worthy, etc.," Price says. If those results hold up in larger studies and for a longer period of time, the approach could make ketamine treatment much more affordable, says, a professor of psychiatry at Baylor College of Medicine and a co-author of the study.
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