Should you mix and match your COVID-19 booster? Experts weigh in

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Should you mix and match your COVID-19 booster? Experts weigh in
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What to know before you mix and match.

Studies like this one have another problem, too."Instead of thousands or tens of thousands of subjects , these are hundreds of subjects. So they're really not powered to make adequate conclusions," Stappenbeck explained."I think they're interesting, but they're not conclusive."

For some people, the potential side effects from the shots may also factor into their booster decision. For example, blood clots appear to be a very rare but serious potential risk from the J&J shot. And those most likely to be effected are women of childbearing age. So if you're in that group, you may want to consider switching over to Pfizer or Moderna, Camins said.

For Lindsay Mann, who got two doses of Pfizer in the spring, the only option for a booster at her pharmacy was the Moderna shot."I would have loved to stay in the same, like, vaccine family," she told TODAY,"but I also just wanted to get it.

Either way, know that there aren't any extra risks related to mixing and matching, Kelen said. Of course, there are the usual risks for temporary side effects and the risks for much rarer and potentially more severe side effects . But, again, those are not extra risks from mixing and matching, they are just the inherent risks from the vaccine itself.

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