Stephanie Pappas is a contributing writer for Live Science, covering topics ranging from geoscience to archaeology to the human brain and behavior.
This feat — described in a study published Oct. 3 in the journal Stem Cell Reports — is a step forward in retinal transplantation. The retina is the layer of light-detecting cells in the back of the eye, and damage and disease to the tissue can cause vision loss and blindness. Such conditions can be difficult to treat. Sometimes doctors can move part of the patient's own retina from its outer edges to the center, but this inevitably leads to blind spots in the periphery.
Mandai and her team grew a retinal sheet from human stem cells and used it to surgically patch the monkey's retina — sort of like applying a patch to torn clothing. The transplant was safe and effective, and the monkey's performance on visual tests improved post-surgery, they reported. The rejection may have been due to the cross-species nature of the transplant, Mandai said."Transplantation of human tissue to a human would have less risk of immune response," she suggested.
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