Scientists have created a mouse embryo that's part human — 4% to be exact. This human-mouse chimera has by far the highest number of human cells ever recorded in an animal, according to researchers.
The hybrid is what scientists call a human-animal chimera, a single organism that's made up of two different sets of cells -- in this case, a mouse embryo that has both mouse cells and human cells.This human-mouse chimera has by far the highest number of human cells ever recorded in an animal, according to researchers. Their experiment suggests that many types of human cells can be generated in mouse embryos, and at a much faster rate than in human embryos.
"We reasoned that if we can make the human pluripotent stem cells behave like the mouse pluripotent stem cells, the human cells should mingle well with the mouse stem cells in a mouse blastocyst," Feng wrote."And that is exactly we found."The team's experiment indicates that the"the genetic program embodied in a mouse embryo and the genetic program embodied in human stem cells can crosstalk pretty well," Feng said.
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