I finished my PhD at the Department of Public Health, Karolinska Institutet in Sep 2010. I did my postdoc at IMM and is currently a research group leader and an Associate Professor at the division of Epidemiology at IMM. My research group, Ageing and Health, concerns the ageing population, the driving force of longevity and old age health, and the consequences of it. I have worked for many years with the national population registers in Sweden and have an interest in the validity of these. I am
Centenarians, once considered rare, have become commonplace. Indeed, they are the fastest-growing demographic group of the world's population, with numbers roughly doubling every ten years since the 1970s.
Nonagenarians, or people in their 90s, and centenarians, ages 100 and older, have long been of intense interest to scientists as they may help us understand how to live longer, and perhaps also how to age in better health. So far, studies of centenarians have often been small scale and focused on a selected group, for example, excluding centenarians who live in care homes.
Twelve blood-based biomarkers related to inflammation, metabolism, liver and kidney function, as well as potential malnutrition and anaemia, were included. All of these have been associated with aging or mortality in previous studies. For example, very few of the centenarians had a glucose level above 6.5 earlier in life, or a creatinine level above 125.
The people in the lowest out of five groups for levels of total cholesterol and iron had a lower chance of reaching 100 years as compared to those with higher levels. Meanwhile, people with higher levels of glucose, creatinine, uric acid and markers for liver function also decreased the chance of becoming a centenarian.
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