Poisonous Australian tree’s agonising sting could unlock new painkillers, scientists say

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Poisonous Australian tree’s agonising sting could unlock new painkillers, scientists say
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The gympie-gympie tree causes brutal, persistent pain in a way ‘never seen before’ – but its unique toxins offer hope for non-opioid relief

tree with a sting so painful that legend says it can drive a victim mad with suffering could be the answer to new non-opioid pain relief.

But looks can be deceiving: folklore says one early settler who mistakenly used the leaves for toilet purposes shot himself to end the agony. Researchers from the University of Queensland studying the toxins in the plant believe it could lead to the development of new pain treatments.The toxins, named gympietides in earlier work by the team, interact with nerves after being injected by fine needle-like hairs on the leaves.

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