Novartis to make U.S. researchers' COVID-19 gene therapy vaccine hopeful

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Novartis to make U.S. researchers' COVID-19 gene therapy vaccine hopeful
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Novartis re-entered vaccine making on Thursday, inking a manufacturing deal with a U.S. team whose COVID-19 candidate relies on technology similar to that of the Swiss drugmaker's $2.1 million-per-patient gene therapy, Zolgensma.

ZURICH - Novartis re-entered vaccine making on Thursday, inking a manufacturing deal with a U.S. team whose COVID-19 candidate relies on technology similar to that of the Swiss drugmaker’s $2.1 million-per-patient gene therapy, Zolgensma.

Human trials are planned this year, said Massachusetts General Hospital and Massachusetts Eye and Ear, which are behind the early stage project, adding vaccine manufacturing at Novartis’s AveXis gene therapy unit will start before Monday. Zolgensma, developed by AveXis for deadly spinal muscular atrophy, works similarly, delivering a copy of a missing gene packed inside AAV to babies whose muscles would otherwise not develop.

“When we evaluated the science of it, we were really enthusiastic,” Lennon told Reuters. “And we believe we’re one of the few companies that actually could provide the product in the time frame...given the urgency of the COVID-19 pandemic.”

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