Thousands of lives could be saved by a new heart disease drug, experts say.
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Cholesterol is a fatty substance in the blood, produced by the liver, which can build up inside the walls of blood vessels, making them narrower and increasing the risk of having a heart attack or stroke.By"silencing" the PCSK9 gene, inclisiran can make the liver absorb more"bad" cholesterol from the blood and break it down.was approved for NHS use last year for a relatively rare disease, hereditary transthyretin-mediated amyloidosis.
And the Department of Health and Social Care says it would prevent 55,000 heart attacks and strokes each year for every 300,000 patients treated.NHS patients who have not had a heart attack or stroke but are at high risk of having one will be invited to take part in the latest trial.Inclisiran will also be assessed for more routine use next year based on evidence from previous trials.
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