A new study carried out in mice, has identified cells that drive the spread of pancreatic cancer and discovered a weakness in these cells that could be targeted using existing drugs. This offers a promising new approach for treating pancreatic cancer.
A new study carried out in mice, led by Queen Mary University of London, has identified cells that drive the spread of pancreatic cancer and discovered a weakness in these cells that could be targeted using existing drugs. This offers a promising new approach for treating pancreatic cancer.and funded by Barts Charity and Cancer Research UK, found that many patients' pancreatic cancer contains cells called amoeboid cells.
While further tests would be needed involving humans to confirm the conclusions, the study suggests that blocking CD73 could be a promising approach for treating pancreatic cancer and the spread of it, especially considering that drugs blocking CD73 have already been developed and are being tested in clinical trials for various types of cancer.
"While the results would need to be replicated in humans, they are very promising in highlighting a potential way of treating the spread of one of the most aggressive and poorly survived cancers."More than 10,000 people are diagnosed with pancreatic cancer in the UK every year, so finding a way to improve its extremely low survival rate even by a little could save many years of human life.
Like all cancers, early diagnosis is key to improving survival rates. For pancreatic cancer, around half of all patients are diagnosed when the disease has already spread, which is one of the reasons for poor survival rates.
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