New research criteria appear to accurately identify athletes in sports such as boxing or martial arts who will go on to develop chronic traumatic encephalopathy.
, the aim of the development of traumatic encephalopathy syndrome criteria was to provide a way to diagnose the condition in living people.is the first longitudinal assessment of the criteria, which researchers say is a small but important step toward determining whether criteria developed only for research purposes may one day be appropriate for clinical use to diagnose TES early and to potentially prevent progression to CTE.
For this study, investigators collected neurologic and cognitive information from 130 active and retired fighters who are participating in the ongoing longitudinal Professional Athletes Brain Health Study.at the beginning of the study. They then underwent annual brain scans and cognitive tests over a period of up to 6 years.Using the NINDS criteria, a panel of four clinicians diagnosed TES in 52 fighters, or 40% of the total cohort.
Analysis of MRI results showed significant differences between groups in brain volume. Among patients who were positive for TES, brain volumes were significantly smaller with respect to the thalamus, putamen, hippocampus, white matter, gray matter, and corpus callosum and were significantly larger with respect to the lateral and inferior lateral ventricles.
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