The results support further research into physiological differences in the brain chemistry of children with and without ADHD symptoms.
stop-signal procedure, while receiving non-invasive transcranial magnetic stimulation pulses to stimulate the motor cortex.
Response inhibition performance was comparable between the two groups, but compared to their typically developing peers, the ADHD group demonstrated deficient short interval cortical inhibition and less task-related up-modulation from rest to action selection. The ADHD group members had slower and more variable “Go” responses and demonstrated 40% less inhibitory signaling to their fingers during the “driving” portion of the exercise and 45% less during the “stopping” portion.
Overall brain engagement was 10% lower within the ADHD group and diminished TRUM and slower reaction time from the state of rest to selecting an action correlated strongly with severity of ADHD symptoms. Gilbert, Donald L., Huddleston, David A., Wu, Steve W., Pedapati, Ernest V., Horn, Paul S., Hirabayashi, Kathryn, Crocetti, Deanna, Wasserman, Eric M. Motofsky, Stewart H.
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