A new paper reviewing the existing studies on long COVID is suggesting that research is still sorely lacking in providing relief for patients.
The world has been grappling with the spectre of long COVID since mid-2020, when some patients realized their COVID-19 symptoms hadn’t fully disappeared — but nearly three years later, how much do we really know about this persistent issue?
“On the basis of more than two years of research on long COVID and decades of research on conditions such as ME/CFS, a significant proportion of individuals with long COVID may have lifelong disabilities if no action is taken,” the authors wrote. But while long COVID could be a matter of months for some patients, for others, long COVID has had debilitating impacts, with symptoms persisting for greater than a year and changing their quality of life dramatically.
The review found that the incidence level had a wide margin, estimated at 10-30 per cent of non-hospitalized cases, 50-70 per cent of hospitalized cases and 10-12 per cent of vaccinated cases. However, it’s still unclear what the incidence of severe cases of long COVID is —meaning those with symptoms measured in years rather than months.
Researchers still haven’t pinned down the cause of long COVID, and “there are likely multiple, potentially overlapping, causes,” the review stated. Researchers also still don’t know much about why some people get long COVID after an acute COVID-19 infection and others don’t. “Many researchers have commented on the similarity between ME/CFS and long COVID; around half of individuals with long COVID are estimated to meet the criteria for ME/CFS, and in studies where the cardinal ME/CFS symptom of postexertional malaise is measured, a majority of individuals with long COVID report experiencing postexertional malaise,” the authors wrote.
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