Lab-created monoclonal antibodies, once a leading way of protecting people against COVID-19, are being sidelined because they don’t work against a growing number of coronavirus variants.
"Monoclonals had their day, like the Model T or the biplane," Carl Dieffenbach, director of the Division of AIDS at the National Institutes of Health and lead of the NIH's Antiviral Program for Pandemics, told NPR."Now it's time to move on."
But the monoclonal antibodies designed for one strain of COVID may not bind to the spike proteins of other strains. Many companies stopped making monoclonal antibodies because they don’t want to spend millions creating a product that will be quickly scrapped, NPR said. Drug companies and scientists are trying to develop new monoclonal variants that won’t become outdated as COVID mutates.
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