Micro-Arousals Can 'Wake' The Brain a Hundred Times a Night, Study in Mice Suggests

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Micro-Arousals Can 'Wake' The Brain a Hundred Times a Night, Study in Mice Suggests
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It might surprise you to know that even during the depths of sleep, your brain cycles through brief bouts of wakefulness.

Far from interrupting a rodent's rest, these occasional spurts of brain activity are part of what make mammalian sleep so refreshing. So far, the results have only been shown in mice, but since they involve some very basic biological mechanisms, the researchers say they could very well translate to humans, too.micro-arousals are"an intrinsic component of normal sleep micro-architecture" in mammals, allowing the memory system to 'reset' multiple times a night.

"You may think that sleep is a constant state that you are in, and then you wake up. But there is a lot more to sleep than meets the eye,""We have learned that noradrenaline [Norepinephrine is a brain chemical and hormone associated with stress and wakefulness. Previously scientists thought NE levels were largely stable during mammalian sleep, but the current study on mice indicates otherwise. In fact, researchers found the greater the swing in NE activity during mouse sleep, the better the rest overall.

In mouse models, NE activity was found to rise and fall continuously during sleep, oscillating every 30 seconds or so. When NE levels descended, researchers noticed that short bursts of electrical activity called sleep spindles gradually built up in the brain. When NE levels began to rise, on the other hand, these spindles were terminated.

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