The cheap, readily available, highly processed food we're consuming too much of is bad for us. An interesting new mouse study has backed up the enduring hypothesis that high fat and sugar diets and cognitive decline such as Alzheimer's are linked.
The team were looking for a mouse model that can tell us more about the intersection between Alzheimer's disease, type two diabetes and obesity, and oh boy did they find it.
"Moreover, obesity and type 2 diabetes are increasingly linked to impaired central nervous system function, by exacerbating psychiatric and cognitive disorders, including mood disorders, cognitive decline and dementias.", this type of finding isn't likely to help anyone with better eating habits, but it is able to give us more tools to be able to investigate this perplexing link, which the team wanted to look into further in mice.
The control mice fed a high fat diet put on weight, had an increased risk of exhibiting anxiety-like behaviors, and showed higher levels of tau in the brain. Tau is important because it's a protein which can becomeFor those mice with the pR5 mutation fed the high fat diet, there was an even larger slew of problems.
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