Findings suggest that at time of T2D diagnosis some might not benefit from metformin as first-line treatment. Dual or other therapy may be preferable. EndoTwitter
The study is also noteworthy in that it demonstrated the feasibility of using electronic health data with a machine-learning approach to discover risk biomarkers, Bielinski, professor of epidemiology at the Mayo Clinic, Rochester, Minnesota, told"We wanted to repurpose clinical data to answer questions...I think more studies using these types of techniques repurposing data meant for one thing could potentially impact care in other domains...
Overall, a total of 43% of patients met one of two criteria for metformin failure by 18 months. Among those, median time to failure on metformin was 3.9 months. Unadjusted failure rates were higher among African Americans, Hispanics, and other racial groups compared with non-Hispanic White patients. However, the racial groups also differed by baseline characteristics. Mean A1c was 7.7% overall, 8.1% for the African American group, 7.9% for Asians, and 8.2% for Hispanics, compared with 7.6% for non-Hispanic Whites.
Of 150 clinical factors examined, higher A1c was the strongest predictor of metformin failure, with a rapid increase in risk appearing between 7.5% and 8.0%.
Malaysia Latest News, Malaysia Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
A nearby galaxy merger may be hiding dual black holes that are 750 light-years apartA nearby galaxy merger may be home to dual black holes, which are situated less than 800 light-years apart.
Read more »
The best dual-monitor wallpapers: nature, space, and gaming | Digital TrendsThis is our list of the best sources for the best dual-monitor wallpapers. They often offer beautiful nature shots, space vistas, and gaming screen grabs.
Read more »
A lasting 'Legacy': The Oceanside Museum of Art celebrates 25 years with dual exhibitions of iconic worksCurator Danielle Deery drew her selections for 'Legacy' from the more than 300 exhibitions that have been presented at OMA since 1997
Read more »
Gina Lollobrigida, known as the face of la dolce vida (Italian film), has diedGina Lollobrigida, the high-spirited actor who had dual careers in Hollywood and Europe and who for many embodied sultry glamour, has died at 95.
Read more »
How Video Games Can Impact Your Heart HealthScientists are just starting to unravel the complex relationship between video games, like Mario Kart, and heart health, but their findings suggest that moderation may be the key.
Read more »
Free Will Is Only an Illusion if You Are, TooNew research findings, combined with philosophy, suggest free will is real but may not operate in the ways people expect
Read more »