Lawrence Faucette, 58, was dying from heart failure and ineligible for a traditional heart transplant when he received the genetically modified pig heart on Sept. 20.
FILE - Lawrence Faucette sits with wife, Ann, in the school's hospital in Baltimore, Md., in September 2023, before receiving a pig heart transplant.According to the University of Maryland School of Medicine, the. Faucette died Monday.
The Maryland team last year performed the world's first transplant of a heart from a genetically altered pig into another dying man. David Bennett survived two months before that heart failed, for reasons that aren't completely clear although signs of a pig virus later were found inside the organ. Lessons from that first experiment led to changes, including better virus testing, before the second attempt.
Attempts at animal-to-human organ transplants - called xenotransplants - have failed for decades, as people's immune systems immediately destroyed the foreign tissue. Now scientists are trying again using pigs genetically modified to make their organs more humanlike. In mid-October, the hospital said Faucette had been able to stand and released video showing him working hard in physical therapy to regain the strength needed to attempt walking.
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