Long COVID: Could mono virus or fat cells be playing roles?

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Long COVID: Could mono virus or fat cells be playing roles?
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Nearly three years into the pandemic, scientists are still trying to figure out why some people get long COVID and why a small portion have lasting symptoms.

This photo provided by Amy Watson of Portland, Ore., shows her during an iron infusion in December 2022. Watson, approaching 50, says she has never had any kind of recovery from COVID-19. She has had severe migraines, plus digestive, nerve and foot problems. Recently she developed severe anemia.

Nearly three years into the pandemic, scientists are still trying to figure out why some people get long COVID and why a small portion — including the three women — have lasting symptoms. Another possible factor: Women are more likely than men to seek health care and often more attuned to changes in their bodies, Klein noted.

She and some similarly ill colleagues connected with Perego on Twitter. “We started sort of coming together because it was literally the only place where we could do that," Pope said. “In 2020, we would joke that we’d get together for Christmas and have a party,” Pope said. “Then obviously it went on, and I think we stopped joking.”

Henrich is among researchers who have found immune markers signaling Epstein-Barr reactivation in the blood of long COVID patients, particularly those with fatigue. Lab tests showed that the virus can reproduce in fat tissue. That raises the possibility that fat tissue could serve as a “reservoir," potentially fueling long COVID.

“We have a good scientific basis together with some preliminary data to argue that we might be on the right track," said Dr. Philipp Scherer.It has been estimated that about 30% of people infected with the coronavirus will develop long COVID, based on data from earlier in the pandemic.

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