Lessons From The Covid-19 Pandemic May Provide Insight Into An HIV Vaccine

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Lessons From The Covid-19 Pandemic May Provide Insight Into An HIV Vaccine
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Infectious disease expert Dave Wessner reports from the 24th International AIDS Conference, where researchers shared ways that Covid vaccine development might help the development of a vaccine for AIDS.

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Finally, and maybe most significantly, broadly neutralizing antibodies, or bnAbs, seem to develop only in a minority of people infected with HIV and then only years after the initial infection. This hinders one of the primary means through which vaccines work.Quite simply, broadly neutralizing antibodies are proteins produced by our immune system that can effectively block infection by genetically and structurally diverse variants of a virus.

The search for an effective HIV vaccine has been a slow, arduous process. But the 40-year struggle has benefited the vaccine field in many ways. We understand the human immune system better because of the work done on HIV. Arguably, the Covid-19 vaccines were developed so rapidly in part because of lessons learned from HIV. Now, perhaps, lessons learned from Covid-19 will impact the development of an HIV vaccine.

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