Scientists have used stem cells to create structures that resemble human embryos in the lab, in a first that has prompted calls for stricter regulation in the rapidly advancing field.
Several different labs around the world have released pre-print studies in the past seven days describing their research, which experts said should be treated with caution as the research has not yet been peer-reviewed.
The first announcement was last Wednesday, when Magdalena Zernicka-Goetz of Cambridge University and the California Institute of Technology described her team's work at the International Society for Stem Cell Research's annual meeting in Boston.On Thursday, the team of Jacob Hanna at the Weizmann Institute of Science in Israel published a pre-print study detailing their own work on stem cell-based human embryo models.
Within a few weeks of each other in August last year, both the Zernicka-Goetz and Hanna teams published papers about their work creating the first embryo-like structures using stem cells from mice. He told AFP that his models had a "placenta, a yolk sac, amniotic cavity" and other embryo features that he said the Zernicka-Goetz structures lacked.
Darius Widera, an expert in stem cell biology at the UK's University of Reading, told AFP that it was best to wait for peer review before comparing the research."We should try to avoid unhealthy hype since this technology is at an early stage -- but already, new guidelines are going to be needed."Both labs said they had developed their embryo models for 14 days, the legal limit for growing human embryos in the lab in many countries.
Cambridge University said on Friday it had launched a project to develop the first governance framework for stem cell-based human embryo models in the UK.
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