But hidden underneath our gums are the dormant buds of a third generation, according to Katsu Takahashi.
This combination of undated handout images received by AFP on November 5, 2024 by the Medical Research Institute Kitano Hospital in Osaka shows before and after images of the regrowth of a tooth in a mouse. - AFPPIX: People with missing teeth may be able to grow new ones, say Japanese dentists testing a pioneering drug they hope will offer an alternative to dentures and implants.
His team launched clinical trials at Kyoto University Hospital in October, administering an experimental medicine to adult test subjects that they say has the potential to jumpstart the growth of these concealed teeth.It’s a technology “completely new” to the world, Takahashi told AFP. Tests on mice and ferrets suggest that blocking a protein called USAG-1 can awaken the third set, and the researchers have published lab photographs of regrown animal teeth.
Angray Kang, a dentistry professor at Queen Mary University of London, only knows of one other team pursuing a similar objective of using antibodies to regrow or repair teeth. “The assertion that humans possess latent tooth buds capable of producing a third set of teeth is both revolutionary and controversial,“ he told AFP.The results of the animal experiments raise “questions about whether regenerated teeth could functionally and aesthetically replace missing teeth“, Zhang added.A confident Takahashi argues that the location of a new tooth in a mouth can be controlled, if not pinpointed, by the drug injection site.
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