Ibogaine can treat addiction – but the race to make it profitable is an ethical minefield

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Ibogaine can treat addiction – but the race to make it profitable is an ethical minefield
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Clinics and scientists around the world aim to turn a profit from a powerful Gabonese plant – but it’s an ethical and legal wild west

have concluded that since ibogaine is a stimulant, it can speed heart rate enough to cause cardiac arrest. That risk is amplified by ibogaine clinics operating largely without regulation and the standards of medical care – such as monitoring heart rate and testing patients for drugs that might interact dangerously with ibogaine – that protect the safety of patients who take it.

Ibogaine can strain the kidneys and liver, but deaths are almost always attributed to its effect on the heartDelix has completed pre-clinical trials and hopes to start human clinical trials in the second half of 2023.

With ayahuasca and psychedelics other than ibogaine, the focus is on psychotherapy. The trips can give people insight into the issues that underlie their addictive behaviors and help them use that insight to get sober. Ibogaine is unique. While it does prompt psychological insights similar to those produced by other psychedelics, it is the only one that also has a physical effect that stifles symptoms of opioid withdrawal.

A nun and girls carrying candles pray with their faces painted white during a Bwiti initiation ceremony.Most iboga sold in the global market has been illegally exported from Gabon, according to Lee White, Gabon’s minister of water, forests, the sea, and environment. Authorities suspect it’s mostly poached by people coming in from neighboring countries and carried on fishing boats that get lost in the heavy sea traffic between Gabon, Cameroon and Nigeria.

“Everyone should have access to this medicine, but in a legal, sustainable and fair way. There is no problem with companies making money, but when they potentially generate huge profits while iboga is plundered from the public domain, that is a big problem,” he said.Tabernanthe iboga

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