The antimalarial drug hydroxychloroquine did not benefit non-hospitalized patients with mild symptoms from Covid-19 who were treated early in their infection, according to a new study
A pharmacy tech pours out hydroxychloroquine pills in May. George Frey/AFP/Getty Images
It was tested in 491 adults in the United States and Canada. Half the patients received a five-day hydroxychloroquine treatment and half the patients received five days of a placebo. The adults were enrolled within the first four days of reporting symptoms, and 56% were enrolled in the trial the first day they reported any symptoms. Doctors monitored symptoms for two weeks.: At the end of two weeks, the study found that there was no advantage to taking the drug.
The University of Minnesota researchers’ first randomized trial, published in the New England Journal of Medicine in June, looked at the drug as a possible post-exposure prophylaxis for adults who had been recently exposed to someone who was positive for Covid-19. It showed hydroxychloroquine did not prevent illness.
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