Human cells help researchers understand squid camouflage

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Human cells help researchers understand squid camouflage
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Squids and octopuses are masters of camouflage, blending into their environment to evade predators or surprise prey. Some aspects of how these cephalopods become reversibly transparent are still 'unclear,' largely because researchers can't culture cephalopod skin cells in the lab. Today, however, researchers report that they have replicated the tunable transparency of some squid skin cells in mammalian cells, which can be cultured. The work could not only shed light on basic squid biology, but also lead to better ways to image many cell types.

. Typically, reflectins clump together and form the nanoparticles, so light isn't absorbed or directly transmitted; instead, the light scatters or bounces off of them, making the leucophores appear bright white.to stably, instead of temporarily, form reflectin nanostructures for which we could better control the scattering of light," says Gorodetsky. That's because if cells allow light through with little scattering, they'll seem more transparent.

In experiments, the team added salt to the cells' culture media and observed the reflectin proteins clumping together into nanostructures. By systematically increasing the salt concentration, Bogdanov got detailed, time-lapse 3D images of the nanostructures' properties. As the nanoparticles became larger, the amount of light that bounced off the cells increased, consequently tuning their opacity.

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