Highly virulent HIV variant found circulating in Europe

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Highly virulent HIV variant found circulating in Europe
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The mutated strain is more severe and more transmissible — but drugs are still effective against it.

, also serve as a reminder that viruses do not always evolve to become less virulent over time. Reports that infections with the Omicron variant of SARS-CoV-2 tend to cause mild COVID-19 symptoms have fuelled the narrative that the virus is becoming less deadly. “This is not how it works”, says Emma Hodcroft, a molecular epidemiologist at the University of Bern. Although HIV and SARS-CoV-2 are different in many ways, “it’s not a given that SARS-CoV-2 will become milder,” Hodcroft says.

The researchers estimated that, without treatment, people infected with this variant would develop AIDS within 2 to 3 years after diagnosis, compared with 6-7 years for those infected with other HIV strains.Using genome sequences, the researchers traced evolutionary relationships between different HIV variants to determine how fast the virus had spread.

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