Genome editor tackles disease that can cause sudden death

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Genome editor tackles disease that can cause sudden death
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Scientists repair a mutation that causes heart-muscle abnormalities and can kill without warning.

A conventional mouse’s heart looks similar to the heart of a mouse engineered to have one copy of a disease-causing gene; both contrast with the heart of a mouse with two copies of the gene.

Credit: A. C. ChaiGenome editing can correct a genetic mutation that can cause a sudden and early death from heart abnormalities, according to a study in mice and in human cells grown in the laboratory

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