FDA OKs New Combo Therapy for Prostate Cancer
."We prospectively designed the MAGNITUDE study to identify the subset of patients most likely to benefit from targeted treatment with AKEEGA and to help us understand how we can potentially achieve better health outcomes for patients."gene alterations, and those patients are more likely to have aggressive disease, poor outcomes, and shorter survival.
lists the recommended dose at 200 mg niraparib and 1000 mg abiraterone once daily in combination with 10 mg of prednisone daily until disease progression or unacceptable toxicity. Patients should also receive a gonadotropin-releasing hormone analog concurrently or should have had bilateral orchiectomy.
Healthcare professionals should report all serious adverse events suspected to be associated with the use of any medicine and device to the FDA's Sharon Worcester, MA, is an award-winning medical journalist based in Birmingham, Alabama, writing for Medscape, MDedge, and other affiliate sites. She currently covers oncology, but she has also written on a variety of other medical specialties and healthcare topics.
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