Exclusive: UK probes Novo's Ozempic, weight-loss drug Saxenda over suicidal, self-harming thoughts

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Exclusive: UK probes Novo's Ozempic, weight-loss drug Saxenda over suicidal, self-harming thoughts
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Britain is reviewing a class of drugs used in a diabetes medicine and a weight-loss treatment sold by Novo Nordisk after some patients reported suicidal or self-harming thoughts, two weeks after similar action by the European Union.

dulaglutide, were also included. Sanofi did not immediately respond to a request for comment on Wednesday.

GLP-1 receptor agonists were originally developed to treat type 2 diabetes. They mimic a gut hormone that suppresses appetite, promoting the feeling of fullness. It said the review would consider safety data including adverse drug reactions reported by patients and clinicians to the MHRA and other medicines regulators that it did not name.

Between 2010 and July 6 this year, the MHRA received 12 suspected adverse drug reactions involving liraglutide also associated with "suicidal and self-injurious behaviour".

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